The St. Louis Cardinals will battle the Boston Purple Sox in a key early-season interleague matchup on Sunday Night time Baseball. The sport would be the second of a day-night doubleheader after Saturday’s recreation was rained out. The Cardinals (4-3), who completed second within the Nationwide League Central at 83-79 a 12 months in the past, will ship righthander Miles Mikolas (0-0, 3.38 ERA) to the mound. The Purple Sox (4-4), who have been third within the AL East at 81-81 in 2024, are anticipated to start out righthander Richard Fitts (0-1, 4.50 ERA). 

First pitch is at 7:10 p.m. ET at Fenway Park in Boston. The newest Cardinals vs. Purple Sox odds from Caesars Sportsbook record Boston because the -124 favourite (threat $124 to win $100), whereas the over/underneath for complete runs is 9. Mikolas’ over/underneath for complete hits allowed is 5.5. Earlier than making any Cardinals vs. Purple Sox picks, make sure you see the MLB predictions from SportsLine’s confirmed mannequin.

The SportsLine Projection Mannequin simulates each MLB recreation 10,000 instances. It enters the 2025 MLB season on a 32-17 roll on top-rated run-line betting picks (+699) that dates again to 2023. Anyone following at sportsbooks and on betting apps might have seen robust returns.

Now, listed below are the mannequin’s three greatest bets for Cardinals vs. Purple Sox on Sunday:

Purple Sox to win (-124)

Boston entered play on Sunday on a roll and had outscored its opponents 24-13 over the earlier three video games. Cardinals pitching has posted a 4.85 ERA via their first seven video games, ninth-worst in MLB. Search for proper fielder Wilyer Abreu to proceed his quick begin to the season. He was hitting .500 via eight video games with two doubles, three homers and eight RBI. Caesars Sportsbook is among the books with the perfect return on this line at -120. 

Over 9 complete runs (-115)

The groups have mixed to attain 9 or extra runs in every of their 5 earlier conferences previous to Sunday. The mannequin offers 5 St. Louis batters at the very least a forty five% probability for an RBI, together with Nolan Arenado, Victor Scott, Alec Burleson, Brendan Donovan and Jordan Walker. Six Boston gamers got at the very least a 52% probability of knocking in a run – Abreu, Rafael Devers, Alex Bregman, Trevor Story, Tristan Casas and Ceddanne Rafaela. The mannequin is projecting 10 mixed runs, because the over hits in over 50% of simulations.

Each groups to attain 3 or extra runs (-142)

Boston and St. Louis entered Sunday with top-10 offenses. The Cardinals led MLB with a .302 crew batting common, whereas the Purple Sox have been tenth at .256. Each groups are additionally top-six in runs scored, with St. Louis third with 51 and Boston sixth with 40. Ivan Herrera entered Sunday tied for second in MLB with 11 RBI, whereas Abreu was tied for twelfth with eight. Over the previous 10 conferences between the groups, each groups have scored three or extra runs in the identical recreation seven instances.

Need extra MLB picks?

You have seen the perfect bets for Cardinals vs. Purple Sox on Sunday Night time Baseball. Now, get picks for each recreation from the mannequin that entered the season on a 32-17 run on top-rated MLB run-line picks.